Avelox side effects

November 12, 2012

Avelox side effects

Avelox is the generic name for the antibiotic moxifloxacin; it is administered intravenously or in 400mg tablet form. Avelox side effects are not dissimilar to others in the same antibiotic family of fluoroquinalones. However one particular Avelox side effect is of more concern – namely the possibility of developing cardiac dysrythmias which may be life threatening. Avelox is a popular treatment for infections where the exact bacterial cause is not known and is therefore referred to as a ‘broad spectrum antibioticÂ’. It is also often used for the treatment of pneumonia.

In patients of all ages, but especially those over the age of 60, there may be increased risk of tendinitis and even tendon rupture. In some patients it may also increase muscle weakness where a pre-existing condition is present.

Commonly Avelox side effects include only nausea, diarrhoea and dizziness. Until you are sure that Avelox does not cause you dizziness you should avoid driving or using heavy machinery. The list of serious side effects is much more substantial, may occur after only one dose and include, as well as those already mentioned, the following -

  • Anaphylaxis – severe allergic reaction which may include hives swelling of the face, itching, breathing difficulty, tightening of the chest.

  • Increased intracranial pressure

  • Toxic psychosis

  • Seizures

  • Suicidal thoughts

  • Depression – or other mood/mental alterations including increased anxiety, nervousness, confusion, restlessness etc. suicidal thoughts or actions.

  • Photo toxicity – over exposure to sunlight should be avoided when taking Avelox, including the use of sun beds.

  • Hypersensitivity

  • Dermatological problems – peeling or blistering skin, noticeable redness

  • Disorders of the blood

  • Liver or kidney disorders – dark urine, pale stools, yellow tinge to the eyes and skin.

  • Loss of appetite and weight gain or swelling.

  • Tremor

  • Trouble sleeping including occurrence of night terrors

  • Development of double vision or other vision disturbances.

  • Persistent headaches and dizziness.

  • Unusual bruising or bleeding

It is important to consult the manufacturers published documentation for a complete list of Avelox side effects before prescribing.

For some patients Avelox side effects may be worsened due to other medications they may be taking including, but not exclusively, haloperidol, methadone, other fluoroquinalones. For these patients extreme caution is required – since the list of these medications is lengthy it is important to fully consult your medical practitioner and/or pharmacist should you be prescribed Avelox and are already taking prescription medication.

It may be that dose modification is all that is necessary to other drugs in your treatment regime – these would include -

  • Warfarin

  • Diuretics

  • Many cardiac medications.

Some antacids and vitamin and mineral supplements may cause Atelox to be less effective and should be avoided whilst taking it if possible.

Caution is also recommended in patients who -

  • Have undergone organ transplant

  • Suffer seizures

  • With advanced liver or kidney disease

  • Those with increased risk of cardiac arrhythmia

It is currently not known whether there is any risk to pregnant or lactating mothers who take Avelox.

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